Warwick Systems Biology Centre

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Warwick Systems Biology Centre (WSB)

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‘The biology of the 21st Century’ Professor Denis Noble, who is a pioneer in the field of systems biology building the first working computational model of the heart and has been given an honorary degree at Warwick, talks about how the future study of biology will change in the 21st Century. Download the podcast here.

PhD studentships are available from BBSRC/EPSRC funded Systems Biology, MOAC and Complexity Doctoral Training Centres. We are interested in receiving applications from students with a mathematical or physical sciences background, or with a background in biology. To find out more please visit us here.

Systems Approaches to Biological Research. The Warwick Systems Biology Centre (WSB) has recently received three large grants from the SABR (Systems Approaches to Biological Research) initiative funded by BBSRC and EPSRC. These are to study (i) the dynamics and function of the NF-kB signaling system (with Prof. M White, Liverpool). (ii) the robustness of plant signaling systems to temperature changes (led by Dr K Halliday, Edinburgh), and (iii) the mechanisms determining the switching between different stress responses in plants. As a results we have available a number of postdoctoral posts for people with a strong mathematical, statistical or computational background. The people appointed to these will be involved in modeling, analysis of cutting-edge biological data and experimental design and will be involved in all aspects of the biological projects. There is also a post for a bioinformatics technician. Anyone interested in any of these posts should contact Professor David Rand (d.a.rand@warwick.ac.uk) as soon as possible for further details. 

Other news ... here 

 The Centre

The University of Warwick has created a new centre in the scientifically exciting and strategically important area of Systems Biology. This will build on the University’s current strengths in the area and involves a substantial investment that includes 12 new posts, a number of secondments, sizeable infrastructure and dedicated accommodation. This initiative is being led by the Department of Biological Sciences, the Mathematics Institute, the Medical School and Warwick HRI.

Systems biology involves developing the understanding of a biological system through the mathematical and computational modelling of the interactions of components of the system, leading to the expression of this understanding in qualitative and quantitative terms. A key feature that distinguishes the modern approach to Systems Biology is the aim of linking modelling with the huge volume and diversity of contemporary cellular and molecular data such as that coming from high-throughput, genome-wide and imaging technologies. Understanding of complex biological processes will allow us to tackle many important problems and will be crucial in addressing an enormously broad range of biological and medical priorities such as disease mechanisms, pharmaceutical drug discovery, drug target validation, and horticulture and agriculture.

Warwick Systems Biology (WSB) is an autonomous research centre that is co-directed by an experimental biologist and a theoretician. It has its own staff, some of who have a joint appointment with another department, and its own dedicated accommodation on the top floor of Coventry House. The theory co-director is Professor David Rand (Mathematics); the experimental co-director is Professor Georgy Koentges (Biological Sciences). Professor Liz Wellington leads the Centre's microbiology activities and will direct the 4m euro SYSMO grant led by the Centre. Other recently appointed staff include David Wild, Jim Beynon, Paul Thornally, Till Bretschneider, Katherine Denby, Magnus Richardson and Sasha Ott. They join the staff seconded from within Warwick who include Nigel Burroughs, Hugo van den Berg and Matthew Turner.

The University already has a thriving programme at the interface between the life sciences and the mathematical and physical sciences which has been led by the Interdisciplinary Programme for Cellular Regulation (IPCR) and the doctoral training centre MOAC (Molecular Organisation & Assembly in Cells) (MOAC). MOAC  is funded by the Life Sciences Programme of the EPSRC. Over an 8-year period it will produce a minimum of 50 PhD postgraduate students with a uniquely broad interdisciplinary training in biology, chemistry, mathematics and computing. Further funding over a 3-year period will fund approximately another 10 studentships per year in our new Systems Biology Doctoral Training Centre. The two DTCs are co-located with WSB.

The Interdisciplinary Programme for Cellular Regulation (IPCR) is a research programme funded primarily by the EPSRC and BBSRC with about 15 main projects in areas such as circadian rhythms, photoperiodism, bioinformatics, the mathematical architecture of gene regulation, plant development, statistical analysis of biological data, cellular signalling, protein transport and cell mechanics.

WSB and the two DTCs are located on the top floor of Coventry House, immediately between Car Park 7 and Warwick Arts Centre. Directions can be found here.

Further information about the Centre can be obtained from Professor David Rand (d.a.rand@warwick.ac.uk) or Professor Professor Georgy Koentges (g.koentges@warwick.ac.uk). Potential applicants to the postgraduate programme should contact the Doctoral Training Centre direct.

Links

IPCR
Systems Biology Doctoral Training Centre
MOAC Doctoral Training Centre
Mathematics
Biology
Statistics
Physics 
Warwick Medical School
Warwick HRI
Warwick

Address:
Systems Biology Centre

Coventry House
University of Warwick 
Coventry CV4 7AL
United Kingdom

Phone:
+44(0)24 7652 3738

Engineering and Physical Sciences Research Council

Biotechnology and Biological Sciences Research Council

 

Page contact: Brent Kiernan Last revised: Mon 8 Dec 2008
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