Global outrage and disgust as ex-hedge funder, 32, buys rights to AIDS drug and raises price 5500% from $13.50 to $750 per pill

Martin Shkreli buys rights to AIDS medication and jacks up prices 5500%

Martin Shkreli, 32, founder and chief executive of Turing Pharmaceuticals, purchased the rights to Daraprim which is used for treating life-threatening parasitic infections - for $55million. He raised the price of the drug form $13.50 per tablet to $750 per tablet. Since the announcement, people across social media have criticized the price increase, but Shkreli has backed the decision, saying that his company 'need to turn a profit on the drug'.

Husband found guilty of first-degree murder after pushing his wealthy wife off a 130ft cliff on their 12th wedding anniversary

Harold Henthorn found guilty after pushing his wife  Toni off a cliff to her death

Harold Henthorn, 59, was convicted of first-degree murder by a federal jury in the death of his second wife, a wealthy Mississippi native, today. Toni Henthorn (pictured left and right, with Henthorn) 50, died when she fell about 130 feet in a remote area where the couple had been hiking on their 12th wedding anniversary on September 29 in 2012. Prosecutors have claimed he also killed his first wife, Sandra Lynn Henthorn (inset, on their wedding day), who was crushed when a car slipped off a jack while they changed a flat tire in 1995 - several months after their 12th wedding anniversary.

Peanut company boss is sentenced to 28 YEARS in prison for knowingly shipping salmonella-tainted peanut butter that killed nine people and sickened hundreds

Stewart Parnell, the 61-year-old former owner of Peanut Corporation of America, was behind a salmonella outbreak in 2008 and 2009 that killed nine and sicked 714 Americans in 46 states.

'I'm a pedophile, but not a monster': Man writes confronting essay asking Americans to 'please understand' the different between pedophiles and child molesters

NEW The controversial op-ed written by Tennessee-based graphic designer and self-described 'pedo' Todd Nickerson appeared on Salon.com, arguing pedophilia is a 'sexual orientation'.

EXCLUSIVE: Bound, bludgeoned with a bat and forced to listen to his wife being raped: The Connecticut doctor who survived horror home invasion and triple murder of his family reveals new details of the tragedy

Connecticut's Dr William Petit who survived home invasion murders reveals horrors in book

Dr William Petit was the sole survivor of the shocking home invasion murders that claimed the lives of his family in 2007. Now a new book reveals the details of the grisly killings of his wife Jennifer, 48, daughters Michaela, 11, and Hayley, 17, as well as how he is moving on with his life. Dr. Petit can't help but wonder 'What if that lock on the bulkhead door had been working properly?' That was the door through which evildoers Joshua Komisarjevsky and Steven Hayes entered the Connecticut home.

One in four women studying at an American university say that they have 'experienced unwanted sexual contact'

Mandatory Credit: Photo by Jussi Helttunen/REX Shutterstock (1388940c).. Model Released - Female rape victim.. Rape victim.. ..

The survey by the Association of American Universities comes at a time of heightened public awareness and increased scrutiny of what schools are doing to combat sexual assault on campus.

Baby boy killed in hot SUV identified: Infant was teacher's cousin staying with her for six weeks

Deltona Middle School teacher Chanda Larson, 38, of Orange City, Florida, left Trenton Cason-Collins inside her sport utility vehicle on Friday, according to a Volusia County Sheriff's spokesman.

'How do you wind the window down?' Revealing the most hilarious questions passengers have asked flight attendants

Cabin Crew 2 1280x960.jpg

Every year, Britain's airports handle millions of holidaymakers, and once on the plane, they like to see their requests greeted with a smile and can-do attitude.

Actor who played C-3PO speaks out about his 39-year feud with R2-D2 after 3ft 8inch star branded him 'the rudest man I have met'

Anthony Daniels, who plays C-3PO, has revealed he and his co-star R2-D2 have not seen eye to eye - both figuratively and literally - for the entire 39-year duration of the Star Wars film franchise.

So what REALLY happened to Dubai's Sheikh Rashid? How billionaire prince was hit by claims of cocaine, sex parties - and a 'roid rage' killing before he died at 33

So what REALLY happened to Dubai's Sheikh Rashid?

The Emirati royal, 33, died of a heart attack on Friday according to the Zabeel Palace in Dubai but Rashid, who was stripped of the title of Crown Prince in 2008, has long been an enigmatic figure. Rashid, pictured left in 2006 with his father Sheikh Mohammed and inset in an official picture, has been beset by allegations of drug taking in recent years and was reportedly sent to rehab by his family in 2009. His brother Hamdan is now Crown Prince (main picture right) while another brother Maktoum (main picture left) has been made deputy ruler of Dubai.

Giving babies iPads is playing 'Russian roulette with their development' says leading psychologist

Dr Richard House, a former senior lecturer at Winchester University, warned that devices such as tablets are 'unnecessary, inappropriate and harmful' for young children.

Teen neighbor, 15, pleads not guilty to rape and murder of 8-year-old 'little angel' Maddy - as her father says he FORGIVES the killer

Adrian Gonzalez, of Santa Cruz, California, is charged as an adult for allegedly kidnapping, assaulting and killing eight-year-old Madyson Middleton. He pleaded not guilty on Monday.

Can bikini-clad women make MEN feel bad about themselves? How female objectification in ads creates low self-esteem for guys

Researchers from the College of Saint Rose and the University of South Florida studied 437 men and women to examine the effects of sexually explicit ads on both genders.

Think twice before shaking hands with a man and keep your toothbrush two metres from the loo to avoid bugs, new book says

Two Businesspeople shaking hands, Close-up of hands

NEW Bacteria plays a central role in our lives - good and bad. A study says only 61% of women and 37% of men wash hands after the loo, so buck the trend and scrub your hands for 15 seconds every time.

Former National Hockey League star Todd Ewen found dead in an apparent suicide aged 49 after long battle with depression

NEW The Stanley Cup winner and father-of-two, from St Louis, died from a 'self-inflicted' gunshot wound to the head over the weekend, said police who confirmed his death is being classed as suicide.

That's what you call an upgrade! Russian billionaire unveils his $400m superyacht which is 300ft high, has eight floors and an underwater observation room - replacing his measly $300m boat

Russian billionaire Andrey Igorevich Melnichenko's yacht is the world's LARGEST

Built for Russian billionaire Andrey Igorevich Melnichenko, 'Sailing Yacht A,' which Mr Melnichenko is thought to have named 'A' to ensure it is listed first in shipping registers, is taking its test voyage in Kiel, northern Germany. The ship is believed to have cost over $400million and is the world's largest sailing yacht. At 468ft in length, with masts nearing 300ft high, the 'mega-yacht,' has eight floors and has an underwater observation room.

How to breathe yourself slim: It sounds potty, but a new book says breathing is scientifically proven to work

Over-breathing could be causing anxiety and obesity, says breathng specialist Patrick McKeown in his book The Oxygen Advantage. Breathing properly could help you lose weight.

The Adventures of Superman star Jack Larson dies at 87 

WESTWOOD, CA - JUNE 21:  Actor Jack Larson arrives at the Warner Bros. premiere of "Superman Returns" held at the Mann Village Theater on June 21, 2006 in Westwood, California.  (Photo by Frederick M. Brown/Getty Images)

The Adventures of Superman star Jack Larson has died at 87. He passed away at his home in Brentwood, California, on Sunday. 

'Rot in hell': Relatives scream in disgust as addict mother of 'Baby Doe' Bella Bond and her boyfriend plead not guilty to her murder

Boston's 'Baby Doe' mother Rachelle Bond and her boyfriend plead not guilty to murder

The mother of Baby Doe and her boyfriend were arraigned in a Boston courtroom this morning. Rachelle Bond (left) pleaded not guilty in the death of her daughter Bella (inset) and was ordered held on $1million bail while the judge ruled that her boyfriend Michael McCarthy (right) would be held without bail after being charged with the young girl's murder. The prosecutor at one point described the horrific events that allegedly led to the young girl's death and how the pair did drugs for days after she was killed, leading to one family member being removed from the court as she stood and up and screamed at McCarthy; 'I hope you rot in hell! I hope you rot in fu**ing hell!'

North Texas town rocked by a powerful house explosion that injured at least five

A home in Waxahachie, Texas, blew up at around 8am Monday, causing two of its occupants to be airlifted to an area hospital for treatment. The blast also damaged nine other houses.

Trial of two teenage girls who 'stabbed their friend 19 times to please Slenderman' is delayed due to appeal on whether it should be heard in adult court

An appeals court is considering if the trial of Morgan Geyser and Anissa Weier should remain in adult court. The girls who are 13, from Milwaukee are on trial for attempted murder.

'I'm sorry to inform you I do not believe in the bible': Rare letter in which secretive Charles Darwin confesses to being an atheist is set to sell for $90,000 at auction

The handwritten note, penned 21 years after publishing The Theory Of Evolution, is believed to be the only concrete evidence in which he discussed his views on religion or God.

Scott Walker quits the White House race: Humiliation for conservative favorite and Iowa front-runner who plunged in the polls

Scott Walker is OUT and calls on other GOP candidates to do the same

Wisconsin Governor Scott Walker officially suspended his campaign tonight citing the toxic nature of the primary and implored others to get out, so a conservative alternative could emerge to beat frontrunner Donald Trump. After a poor debate performance, Walker's path to the White House was blocked by low fundraising potential and lower poll numbers.

TV news wars heat up over Hillary Clinton's Sunday CBS interview as MSNBC anchor insists it was 'textbook planned-out' and scripted - but CBS News insists 'they're wrong!'

Morning Joe Panel Discuss Clinton's ?Textbook Planned Out? Face The Nation Interview

Clinton claimed four times on 'Face the Nation' that she had been 'allowed' to keep official government emails on a private server, but CBS's John Dickerson never asked who had given that permission.

Hillary increases her lead over Bernie Sanders - but Joe Biden could cut into her numbers and she's under water in New York for the first time

MANCHESTER, NH - SEPTEMBER 19:  Democratic presidential candidate Hillary Clinton raises her arms stands on stage during the New Hampshire Democratic Party Convention at the Verizon Wireless Center on September 19, 2015 in Manchester, New Hampshire.  Challenger for the democratic vote Sen. Bernie Sanders (I-VT) has been gaining ground on Clinton in Iowa and New Hampshire.  (Photo by Scott Eisen/Getty Images)

Without Joe Biden in the race, Hillary has more than twice the support of Bernie Sanders, 57-28, in a small national poll. If the VP runs, that gap closes to 42-24 with Biden entering the race at 22 per cent.

Trump launches video bomb on Jeb with mashup of immigration clips - and a hint that he's still 'confused' from smoking dope

Republican presidential candidate, businessman Donald Trump holds a Bible as he speaks during the Iowa Faith & Freedom Coalition's annual fall dinner, Saturday, Sept. 19, 2015, in Des Moines, Iowa. (AP Photo/Charlie Neibergall)

The billionaire's new video mocks Jeb for saying illegal immigrants commit 'an act of love' and claiming the term 'anchor babies' refers mostly to Asian children.

CROCS on the red carpet! The stars who missed the mark with their unusual outfits at the 2015 Emmy Awards - but who made the footwear faux pas?

Emmys 2015's worst dressed stars on the red carpet

There were ill-fitting gowns and eyesores galore on the 2105 Emmy Awards red carpet this year and the likes of (L-R) Amy Schumer, Heidi Klum, Elisabeth Moss, Sophie Turner and January Jones all missed the mark when it came to red carpet dressing. But making the biggest fashion faux pas was one male star who brought out his Crocs for TV biggest night, inset.

Family of comedian killed in crash that left Tracy Morgan with brain trauma blasts the star for failing to mention his mentor in Emmys speech... and reveal he hasn't been in touch at all

NEW The family of comedian James McNair, 62, who died in the crash that left Tracy Morgan with serious injuries, have blasted Morgan for failing to mention his mentor in his Emmys speech last night.

'You make me nervous': Terrence Howard has awkward kiss with Taraji P Henson in yet another uncomfortable award show appearance

Terrence Howard's growing list of ex-wives probably chortled at his Empire co-star's reactions at the Emmy's on Sunday night. The 46-year-old had yet another awkward award show appearance

Soap star rants against Viola Davis using the Emmys for 'racial opportunity' after her stirring acceptance speech on the prejudice faced by black actors

Soap star Nancy Grahn - who attacked Viola Davis after she became the first African-American woman to ever win the Emmy for Lead Actress in a Drama Series at Sunday's Emmy Awards - has apologized.

Emmys draws record low TV audience as 11.9 million viewers tune in (that's almost four million less than last year)

LOS ANGELES, CA - SEPTEMBER 20:  Host Andy Samberg speaks onstage during the 67th Annual Primetime Emmy Awards at Microsoft Theater on September 20, 2015 in Los Angeles, California.  (Photo by Kevin Winter/Getty Images)

Preliminary Nielsen ratings data on Monday showed that just 11.9m Americans watched Sunday's Emmy Awards telecast hosted by Andy Samberg on Fox.

Thrown from bridges, horrifically mutilated, raped or simply 'disappeared': Inside the Mexican state where 900 women have either vanished or been murdered and 1,200 raped in a single year

Mexico's Guerrero state where thousands of women are murdered or raped each year

WARNING: GRAPHIC CONTENT Female mayor Maria Santos Gorrostieta (top right), aspiring actress Carmen Esparza (top left) and politician's daughter Isarve Cano Vargas (bottom right) are among the thousands of women (inset) murdered in Mexico every year. MailOnline visited the country's most deadly state, Guerrero, considered the most dangerous place for women in North America. Just one of the locals who have had their lives ripped apart there is Ahilin Quiñones, 19, whose mother Aide Nava (together at Ahilin's wedding day, bottom right), father and brother have all been murdered by cartel members in her home town of Iguala.

Hundreds of millions of iPhone users at risk as Apple store is hit by its first major hack: Malicious codes found in some of China's most popular Apps

The security breach took place after hackers convinced legitimate developers to use a tainted and counterfeit version of Xcode - the software provided by Apple for creating iOS and Mac apps.

The truth about the Big O: Anonymous women reveal the secrets of their sexual desires on graphic viral blog

A Tumblr called 'How To Make Me Come' has been set up by 27-year-old writer who goes by the non de plume Sylvia. So far 72 nameless contributors have written essays on their sexual experiences.

REVEALED: How DNA finally led police to murder suspect 30 years after a 15-year-old schoolgirl was brutally raped and killed

Detectives hunting for the killer of Kristina Wesselman, 15, have arrested Michael Jones of Champaign, Illinois, after his DNA provided a match with evidence from the scene of the 1985 attack.

Pope Francis is greeted by thousands in eastern Cuba as U.S. prepares for his arrival and the 'largest security operation in history'

Pope Francis is greeted by thousands in eastern Cuba

Francis is travelling to the city of Holguin on the anniversary of the day in 1953 when he says he decided to become a priest. Francis leaves Havana after meeting Fidel Castro. The Vatican invited Cuban dissidents to meet him but they said security agents detained them. After he moves on to Santiago, Cuba, Francis will head to Washington for the U.S. leg of his two-nation trip to the former Cold War foes.

Catholic congressman BOYCOTTING Pope Francis visit over his 'leftist' global warming views

At least one Catholic congressman is saying nope to the Pope over the issue of global warming. Rep. Paul Gosar said he won't attend Francis' speech before Congress on Thursday.

Senate Republicans gear up for 'show vote' on late-term abortion ban as Pope Francis comes to town

Just two days before Pope Francis makes his long-awaited visit to Capitol Hill, Senate Republicans have scheduled a bill to restrict abortions past the 20th week of a pregnancy.

'I'm humiliated for myself and my family': Hobbit actor Manu Bennett breaks silence over arrest for assault at a Comic Con after-party

Actor Manu Bennett, who played the character Azog in the Hobbit trilogy, has addressed news of his arrest for assault which took place last week at Alamo City Comic Con in Texas.

Soiled beds and ransacked rooms - are these the worst hotel guests EVER? The shocking damage hell-raisers leave behind

Soiled beds and blocked toilets... are these the dirtiest hotel rooms EVER?

Soiled mattresses, gag-inducing blocked toilets and a deluge of festering takeaway dishes; these are the sickening scenes left behind after a series of guests. In one incident, six fraternities and sororities at a hotel in Michigan caused an estimated half a million dollars worth of damage by smashing ceilings and destroying furniture.

America's most oversensitive generation: Modern students are more PC than ever before and are 'killing off free speech on U.S. campuses'

Today's generation of American college students are more sensitive than their predecessors - and this could have a disastrous impact on both their education and mental health, experts warn.

Mother driving her young son jumps from a moving car after seeing a SPIDER and causes collision with a school bus

Woman causes wreck after seeing a spider and jumping from a moving car

Angela Kipp, 35, of Indiana, had been backing her Dodge Avenger out of her driveway when she saw a spider on her shoulder, panicked and leaped out of the moving vehicle in fear.

Skype is STILL offline: Glitch prevents users from making calls and logging in, and the company has yet to find a fix

Skype says the glitch makes users appear to be offline even when they are online, meaning they cannot make calls to each other. Some users have also had problems signing in to their accounts.

ESPN analyst Kirk Herbstreit gets in Twitter feud with real-life 'The Blind Side' blonde after she calls him out on his commentary

ESPN analyst Kirk Herbstreit gets in Twitter feud with real-life ‘The Blind Side’ blonde

ESPN analyst Kirk Herbstreit (left) has apologised to Leigh Anne Tuohy (right) after hitting back at her jabs over his comments during Saturday's night game between Ole Miss and Alabama. Despite the University of Mississippi's Rebels scoring a 43-37 victory over Alabama, fans took to Twitter to air their frustrations over Herbstreit's commentary during the game at the Bryant-Denny Stadium in Tuscaloosa. Critics included Mississippi fan Tuohy, who was played by Sandra Bullock (inset) in 2009 sports biopic The Blind Side. 'I'm so sick of @KirkHerbsreit and @cbfowler acting like we were just lucky to be on the same field as Bama,' she tweeted. In a reply that he has since deleted, Herbstreit told Tuohy: 'You're embarrassing yourself. Please stop and enjoy your victory. And to think I was a fan of Blindside.'

Move over Tesla: Apple is working on an electric car for launch in 2019, claims report

The company is tripling the number of engineers on the project, code-named Titan, and has set a 'ship date' for within four years, according to a Wall Street Journal report.

VW stops selling diesel cars in US after firm rigged emissions tests on up to 500,000 vehicles as CEO says sorry for 'broken trust' 

US regulators found Volkswagen used software that allowed its diesel cars to release fewer smog-causing pollutants during tests than in real-world driving conditions.

Love that will break your heart: 92-year-old man serenades his dying wife with a love song in tear-jerking video

92-year-old man sings to his blind and dying wife a love song in tear-jerking video

Howard, 92, is seen singing the love song You'll Never Know to his dying wife, 93-year-old Laura, as she lies on a hospital bed in hospice care. The couple's granddaughter, Erin Solari, captured the tender moment in a Facebook video, which has earned more than 3.6 million views since she posted it on September 12.

The human tide: Waves of migrants keep coming as Hungary warns millions are 'breaking down the doors' of Europe

In a full-page advert in several Lebanese and Jordanian newspapers, the government said 'the strongest possible action is taken' against people who attempt to enter Hungary illegally.

Precious cargo: Desperate Syrian family risk the lives of their eight-month-old twins to make the perilous journey across the sea to Lesbos

The babies arrived on Eftalou beach on the Greek island of Lesbos today in a rubber dinghy after crossing the Aegan Sea from Turkey with their parents after they fled from Syria.

Touching moment Cristiano Ronaldo walked onto Real Madrid pitch holding hand of Syrian refugee who was tripped by Hungarian camerawoman 

The club invited Zaid Abdel-Muhsen Alghadab, his father Osama and brother Mohammad to the Spanish capital as part of their campaign to support refugees arriving in Europe.

Muslims are transforming Europe, says Art Garfunkel in warning over dangers of mass migration

Art Garfunkel attends the 25th Anniversary Summerstage Gala "The Music Of Simon & Garfunkel" at Rumsey Playfield, Central Park on June 8, 2010 in New York City.
25th Anniversary Summerstage Gala - "The Music Of Simon & Garfunkel"
Rumsey Playfield, Central Park
New York, NY United States
June 8, 2010
Photo by Bobby Bank/WireImage.com
To license this image (60686617), contact WireImage.com

Art Garfunkel, who was one part of the pop duo Simon & Garfunkel, has highlighted how an influx of Muslims from war-torn countries including Syria could change the nature of Europe.

Russia's involvement in Syria escalates as US accuses Moscow of flying drone surveillance missions over the war-torn country 

Russia launched drone surveillance missions over Syria, according to U.S. officials. The U.S. and Russia are in discussion as to how to avoid 'accidental interactions' in Syria's airspace.

Senseless slaughter, corruption and broken promises of money and glory: Landmark report reveals why growing numbers of foreign fighters are defecting from ISIS

WARNING: GRAPHIC CONTENT Accounts of 58 deserters claim followers have grown tired of the executions (pictured), broken promises of money and the boredom of life under ISIS rule.

'You don't understand weddings!': Precocious 4-year-old tells dad he must take her flower-girl duties VERY seriously in hilarious video

Four-year-old tells dad he must take her flower-girl duties seriously

Four-year-old JoJo has revealed in a hilarious YouTube video that she takes her flower girl duties so seriously that she wants to make sure her dad does not embarrass her on the big day. 'You're going to see what weddings look like,' JoJo tells her dad in the 96-second clip, which has attracted more than 600,000 views since it was posted on September 14.

Is it wrong to keep cancer secret from your loved ones? After Jackie Collins hid her breast cancer from sister Joan for six years two writers give their contrasting views 

NEW Jackie Collins kept her breast cancer secret from the world, including her older sister Joan, throughout her six year battle with the disease. But was she right to do so, ask two writers?

I refuse to take the Angelina gene test: Renee's sister died of breast cancer and her mother and aunts have battled it. So why does she refuse to be tested?

Renee Maguire, 39, believes a raw food diet will stave off breast cancer. Despite having a 40 to 50 per cent risk of developing it she won't even go for regular mammograms as her doctors have advised.

Why that spare tyre makes you age faster: We all know flabby tums are bad. But a new book has an even more worrying revelation 

Big and curvaceous women at swimming pool

NEW Author Bill Gifford discusses how staying at a healthy weight could help to prolong life. His new book Spring Chicken: How To Stay Young suggests exercise and standing up as ways to achieve this.

Is having a wire stuck in your neck the best way to beat piles? New ways to treat this common problem are much less invasive

Rear view of three people sitting on bar stools

NEW Half of the British population suffer from piles at some point. New cutting edge treatments that are less invasive and potentially less painful, including one that zaps piles with electricity.

Military academy attended by Donald Trump and John Gotti closes after 126 years due to bankruptcy

The New York Military Academy was closed for good last Monday, despite promises of remaining open. It will be auctioned off at the end of the month for a minimum bid of $9.5 million.

'I lost part of my heart and the father of my sweet babies': Fox News commentator's touching tribute to her White House staffer husband who died in a charity bike race

Conservative commentator and Fox News contributor Mary Katharine Ham took to Instagram Sunday to honor her husband, White House aide Jake Brewer, who died in a charity bike race this weekend.

China scandalized by video that captures the moment a Communist official tried to strip a woman NAKED inside local restaurant

A Chinese government official from Jiangsu province, east China, got expelled after scandalous videos of him stripping his female companion emerged on Chinese social media.

Pictured: The moment ABC reporter Gio Benetiz asked his boyfriend to marry him in a fairytale proposal in front of the Eiffel Tower

ABC reporter Gio Benitez asked his boyfriend to marry him in front of Eiffel Tower

ABC News reporter Gio Benitez, 29, had a local photographer capture the moment he got down on one knee in front of his boyfriend, lifestyle blogger Tommy DiDario, and asked him to marry him on a rain-washed terrace overlooking Paris' most famous landmark. DiDario shared more candid photos from the proposal, including a touching snapshot of his and Benitez's intertwined hands showing off their matching rings.

Pregnant? Steer clear of Mississippi and New York: Experts reveal the worst states to have a baby based on cost and level of health care

Wallethub ranked the 50 states and the District of Columbia according to budget, health care, and 'baby-friendly environment'. Americans pay the highest birthing costs in the world.

How cocaine can rot skin and turn ears BLACK: Drug is now routinely cut with cattle de-wormer which eats away at flesh

A 42-year-old woman arrived at Saint Francis Hospital in Rotterdam with leg sores (pictured bottom left) due to cocaine being cut with the cattle de-wormer Levamisole, known to rot human flesh.

The world's richest sisterhood? Taylor Swift's 'girl squad' earned $102.5 MILLION between them last year (and the more they hang out, the richer they get) 

Taylor Swift's girl squad is already the world's most famous friendship group...but now the singer's model pals are watching their bank balances grow as fast as their Instagram followers.

What REALLY happens when you have a sex change? One man's searingly honest account of how he relinquished his life as a woman after 15 years of emotional turmoil

Kirone McCaffrey, 25, from Dagenham, England underwent a series of female to male gender re-assignment surgeries between 2012 and 2015 and now says he feels like 'who he is supposed to be'.

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Biting off more than he can chew! Industrious New York City RAT drags entire pizza slice down subway stairs

Pizza rat Industrious New York City rat drags entire pizza slice down subway stairs

New York City is well-known for its rats and its pizza and one industrious rodent wanted to bring the two iconic Big Apple images together. Introducing: Pizza Rat. Not only does this very hungry vermin unite two things synonymous with the city, it does so on the New York City subway. A straphanger with an iron stomach and a cell phone camera recently caught the cunning critter as it labored to drag a full slice of New York City pizza down the subway platform stairs.

Dirty nappies, gnarled toenails and discarded half-eaten sandwiches: Latest passenger-shaming photos show the most disgusting habits of air travelers

It seems some fliers still haven't quite got the hang of travelling in style. Here are the latest photographs of the horrors faced at 35,000 feet.

The video that will send chills down every parents' spine: YouTube actor lures three boys to a house after 'grooming' them online to expose the dangers of social media

YouTube actor Coby Persin posed as 15-year-old Amanda Green and used the internet to lure three teenage boys in the New York area to potential danger in just 24 hours.

Heroic pastor and congregants wrestled the gun away from church shooter who planned to kill his girlfriend and their infant son

Pastor Earl Carswell and members of his Oasis Tabernacle Church in East Selma, Alabama helped take down an attempted murderer on Saturday.

Did this eight-year-old predict the Chilean earthquake? Schoolboy wrote a warning essay hours before because he felt a tsunami was 'going to happen'

Carlos Perez from Argentina, penned the essay called 'Tsunami in Chile' saying he had a feeling people would have to flee their homes and that a helicopter would rescue them.

Skeletons in her closet! Transsexual freak-show performer with BONES tattooed on her face is arrested on marijuana charges

Transsexual performer Mara Paradox is arrested on marijuana charges

Transsexual performance artist Mara Paradox, of Lubbock, Texas, is seen in her mugshot from Saturday with a skull tattoo on her face, inked eyeballs and a row of horns on her forehead. Born Chance Davis, Mara Paradox has been part of The Traveling Freak SideShow since January. Before landing that gig, Paradox had been performing with the Venice Beach Freakshow, where her act included eating glass, hanging hook from her eyelids and stretching out on a bed of machetes.

'They're together in heaven': Sister-in-law reveals she talks to dead family from beyond at packed funeral for family of five found dead in murder suicide at lakeside Minneapolis mansion 

Minnesota's Short family killed in gruesome murder-suicide are laid to rest

The Minnesota family that was killed in a gruesome murder-suicide was laid to rest over the weekend (left). Brian Short, 45, his wife Karen, 48, and their three children - son Cole, 17, and daughters Madison, 15, and Brooklyn, 14 (inset) - were remembered by friends and family in an emotional service. Friends of Brian (right) also took time to speak about what an amazing man he was and how much he loved his family - despite the fact that he shot them all dead in their bedrooms before turning the gun on himself.

Have you been saying it wrong? Buyers incorrectly pronounce Nutella... as the brand reveals it DOESN'T start with 'Nut'

The official pronunciation of the hazelnut chocolate spread is 'new-tell-uh', according to the Nutella website. The brand explained the correct way to say it on their website under FAQs.

Washington D.C. Holocaust museum unveils genocide predictor tool as it identifies countries most likely to kill their own people 

Experts at the Holocaust Memorial Museum in Washington DC want to use the system to produce early warnings that can help governments decide where to concentrate their efforts.

So THAT'S why cold weather makes you ill: Science says our genes alter their behaviour to suit the season

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Some conditions have always worsened and developed when the temperature drops. Now scientists say your genes alter their behaviour with the seasons.

ASK THE DOCTOR: My cholesterol's fine so why am I on statins? 

Cold hearted pills

A readers asks why he's been prescribed statins when his cholesterol is fine, and Dr Martin Scurr advises that's a preventative measure. He says that schools must teach domestic science.

You really CAN die of a broken heart: Doctor says the loss of a loved one is one of the stresses that can cause cardiac failure

Dr Michael Ward (shown) from Sydney revealed the dangers of 'broken heart syndrome' and said it could be triggered by upsetting events such as bereavement and divorce.

Liver transplant patient becomes the third to die after contracting mold infection at hospital in Pittsburgh

An investigation is underway after three transplant patients contracted fungal infections at a hospital in Pittsburgh, Pennsylvania and later died.

Group of black lawyers claim Texas bar made them and other minorities pay cover charge - but let white revelers in for free

Brandon Ball, 32, and his friends, Dan Scarbrough, 42, and Ken Piggee, 43, were ordered to pay a $20 cover charge after turning up at Gaslamp - a swanky lounge in Houston, Texas - on September 11.

California wildfires destroy 1,600 homes and leave six people dead after they tear through the state

The total number of homes destroyed in two wildfires burning in Northern California to nearly 1,600, the California Department of Forestry and Fire Protection said.

American woman, 37, who became the first female to captain a 91,000 ton cruise vessel reveals 'when guests meet me they're pleasantly surprised'

Kate McCue, 37, took the helm of her maiden voyage on the Celebrity Summit on Sunday as it set sail to New England and Canada. She was in charge of more than 2,000 passengers and a crew of almost 1,000.

Brought to you by the letter I! Samsung's Serif TV is inspired by a font

The Serif TV set is designed by Paris-based brothers Ronan and Erwan Bouroullec and is inspired by the letter 'I', coming in three sizes which turn the television into a piece of furniture.

Fisherman records his OWN shark attack: Man films his injuries after he was forced to swim for his life when a 13ft tiger shark tore a chunk out of his leg

Haiwaiian victim of shark attack posts graphic video of his injurie

WARNING GRAPHIC CONTENT: A man has shared a graphic video of the injuries he suffered after being attacked by a shark. Braxton Rocha of Kapaau, Hawaii was spearfishing approximately 60 yards off the coast on Sunday afternoon when a 13-foot tiger shark bit him on the leg. The 27-year-old then somehow managed to swim safely back to shore and get help while also filming a video of the very big - and very deep - gash on his leg.

Facebook COO Sheryl Sandberg drafted in by Pentagon to launch 'Lean in' groups that bring women and minorities into leadership

ARLINGTON, VA - SEPTEMBER 21:  Facebook Chief Operating Officer and founder of LeanIn.Org Sheryl Sandberg (L) and U.S. Defense Secretary Ashton Carter thank the female members of the military who participated in a 'Lean In Circle' at the Pentagon September 21, 2015 in Arlington, Virginia. Carter announced that the Department of Defense will now allow and encourage men and women in the armed forces to form and participate in 'Lean In Circles,' small groups of people who meet regularly and offer peer support while talking openly about gender issuses.  (Photo by Chip Somodevilla/Getty Images)

Sandberg, author of Lean In: Women, Work And The Will To Lead, has spearheaded 24,000 circles in 120 countries in a bid to counteract gender bias in the workplace.

SEBASTIAN SHAKESPEARE: No oil painting! So why DID Rod buy it?

The stern subject of An Elegant Woman, by the 19th-century French artist Hippolyte Casimir Gourse, has been given pride of place above the fireplace at Rod Stewart's home in Beverly Hills.

New execution date set for the only woman on Georgia's death row after it was postponed TWICE

Kelly Gissendaner 
http://www.dailymail.co.uk/news/article-2976796/Execution-woman-Georgia-s-death-row-DELAYED-minute-drug-used-lethal-injection-cloudy.html

Kelly Renee Gissendaner, convicted of murdering her husband, was first sentenced to receive the lethal injection in February and then in March. Now, it has been moved to September 29.

It's a brushroom! Body scrubbing brush sprouts two MUSHROOMS overnight to the horror of its owner 

Social media user Bantrlicious walked into the bathroom one day to find a pair of tiny mushrooms sprouting up from a scrub brush, and subsequently posted a photo of the scene on Reddit.

Why women should NEVER apply their make-up on the move: Sudden jolts while on trains and buses can 'scratch the eyes and and trigger damaging infections'

Never apply make-up on the tube, wear eyeliner only on the outside of the eyelids and never share make up brushes, experts from the College of Optometrists warn.

Woman finds venomous 1.4m red-bellied black snake in her car bonnet and DRIVES off... until it pops up onto her windshield

NEW Tamara Duff got the fright of her life when the retile hitchiker appeared while she was driving the Bruce Highway on Queensland's Sunshine Coast, pulling over to call a snake catcher for help.

'Mouth the letter U for a sensual look': Denise Richards and Tiffani-Amber Thiessen teach girls how to pose for the camera in hilarious 80s video

Denise Richards and Tiffani-Amber Thiessen teach girls how to model pose in 80s video

The montage features cringe-worthy clips of models demonstrating how to pose for photos in the 80s. Denise, now 44, and Tiffani, now 41, appear as young models in the amusing video, which provides how-to tips for aspiring models and actors.

Domino's customer returns $1,300 he found inside box of wings and is rewarded with free pizza for a year

Mike Vegas of Berkeley, California, ordered pizza and wings over the weekend and was going to relax and enjoy the food during his day off but he ended up finding $1,300 with his order instead.

Is this the world's oldest real house? Vast stone building in 7,500-year-old Bulgarian complex may have had two floors

The remains of the settlement, which is thought to have collapsed due to an earthquake, were uncovered on the 'big island' of Durankulak Lake in the North East of Bulgaria.

Olympic gold medalist and former pro wrestling champ's brother is charged with homicide after he 'killed his wife because they argued about drinking vodka'

Allegheny County homicide detectives said 62-year-old David Angle was arguing with 57-year-old Donna Angle about drinking vodka at the house in Dormont, Pennsylvania, where they had lived for many years.

Married father lucky to be alive after losing both legs in an animal parts processing machine - and he's determined to walk again for new twins arriving in February

John Vrana and his wife, Ashley 

LINK TO:
https://www.gofundme.com/newlegsforjohn

John Vrana, 32, a married father of two girls with twins on the way, was working at his family's Utah factory when he lost his balance and tumbled into a machine used to render animal parts.

Throw like a girl: Texas high schooler becomes first female in school's history to make varsity football team

Reilly Fox is first female to play varsity football at R.L. Paschal High School in Texas

Reilly Fox (No 89, left) made her debut for R.L. Paschal High School in Forth Worth, Texas, on Saturday night (right) during her squad's third game and connected on three extra points during a 76-8 blowout victory over Dallas Molina. Fox also became the Fort Worth Independent School District's first female football player in 15 years. She made the team by showing her coach she could hit field goals from more than 40 yards out with consistency. Fox's parents Eric and Karen could not be happier to see their daughter succeed on the football field.

He might be singing Jailhouse Rock: Man in an Elvis wig with semi-automatic pistol raids a winery tasting room

California police are searching for a man accused of robbing the Monarch Grove Winery tasting room in Grover Beach on Sunday of $400 while wearing an 'old man' mask and an Elvis wig.

Adult Obesity rates top 30 per cent in nearly half of all states across America

The results, from a telephone survey show obesity rates stayed about the same in 45 states last year. However, there were small increases in Kansas, Minnesota, New Mexico, Ohio and Utah.

Shocking moment teenage boy 'PUNCHES female bus driver in Iowa after he accuses the woman of racism during fare dispute'

The 15-year-old black student, who has not been named, was apparently captured on surveillance video punching the bus driver as he exited a Citibus in Davenport, Iowa, last Tuesday afternoon.

An end to puddles? Bizarre 'thirsty' concrete sucks up hundreds of gallons of water in less than a minute

Topmix Permeable concrete sucks up hundreds of gallons of water in less than a minute

A video of a test of Topmix Permeable concrete, developed by Birmingham based Lafarge Tarmac, shows 880 gallons of water vanishing without trace(main picture). The pioneering concrete could help to tackle flash flooding in paved urban areas by preventing water from running off the surface. It could also combat puddles on pavements and cyclepaths as the porous top layer allows water into a rubble layer below, which helps to 'store' the water (as illustrated in the graphic on the top right)

Drunken Indian man is buried alive after falling into a hole while returning home... before construction workers built a ROAD over him

road-constructed-over-man_650x400_71442822227.jpg

NEW Latori Lal, 45, had fallen into the hole in Katni in Madhya Pradesh state, on Friday night, and when road workers arrived the following morning, they failed to notice Mr Lal, and filled the hole with tar.

U2 concert in Stockholm is abandoned after reports man 'armed with a gun was let inside while disguised as a policeman'

The man was let into the U2 concert at The Ericsson Globe Arena in Stockholm last night with a gun after he claimed to be a policeman who had 'forgot to leave the gun at work', it has been claimed.

South African police discover 21 pieces of female genitalia in Danish man's FREEZER after he drugged his own wife and mutilated her

A Danish man living in South Africa has been arrested after police claim to have found 21 pieces of female genitalia stashed inside his freezer alongside anaesthetic, photographs and surgical tools.

Grandmother who needs a new kidney resorts to posting signs in her car and at the side of the road in a bid to find a potential donor willing to her help

Linda Deming, 63, from Pownal in Maine, has stage three kidney disease and is desperate to find a new kidney as she currently has to rely on dialysis treatment three times a week.

Alleged internet pirate Kim Dotcom vows to fight for web freedom as he faces court in New Zealand to learn if he will be extradited to the U.S.

Seated comfortably on a special leather arm chair in a New Zealand court on Monday, Internet tycoon Kim Dotcom will shortly know whether he will be extradited to the U.S. to face charges.

Smacking the ground and threatening to attack: Man records scary encounter with brown bear hiding under his PORCH

Man records shocking encounter with brown BEAR hiding under his house

The video shot in America shows the animal resting under some wooden decking when the owner of the house disturbs it with his camera. Filming the brown bear, while looking for a way to remove it from his property, Vance Hopkins faces off with the animal in one very intense encounter that sees the bear threaten to attack him a number of times.

Armed robber tells Pennsylvania pizza clerk he's having a 'bad day' before stealing a bag of cash

Police say a shotgun-wielding robber told a southwestern Pennsylvania pizza shop clerk he was having a 'bad day. The man entered the Fox's Pizza shop in Hibbs and demanded cash.

CNN poaches foreign correspondent Clarissa Ward from CBS News as their senior international correspondent

Award-winning foreign correspondent Clarissa Ward is joining CNN, the network announced Monday. After four years at CBS News, she will be an international reporter based in London.

North Korea expands space for women in its notorious gulags after large numbers were forcibly returned from China after escaping from the regime

That is the finding of a new report by a human rights group which claims 'scores of thousands' of prisoners have died in the camps over the years, despite North Korea denying existence of the gulags.

More than 4,000 of South Africa's most dangerous prisoners are evacuated from infamous Pollsmoor Prison after two inmates died from a disease spread by rats

Murderers, rapists and violent gang leaders are being moved at gunpoint in a massive, high-risk operation at Pollsmoor Prison, where Nelson Mandela spent part of his incarceration.

Plane journeys set to become A LOT noisier: Lufthansa signs deal to allow phone calls and internet access during flights, with British Airways likely to follow suit

Germany's Lufthansa signed a deal allowing passengers to use their handsets on board from next summer. Passengers will be able to check their emails and log onto Facebook.

Make a list, stick to a budget and shop now: The 10-point guide on why parents should start planning Christmas TODAY to avoid a New Year debt hangover

EXCLUSIVE: With just 94 sleeps until Christmas, are you prepared for frugal festivities? FEMAIL's money expert Kalpana Fitzpatrick reveals top 10 tips to help you have a budget-friendly Christmas.

Does this bacteria hold the key to the 'fountain of youth'? 3.5-million-year-old Siberian specimen boosts longevity and the immune system

The bacteria, seen as a potential elixir of life, was found in 2009, embedded in ancient permafrost at a site known as Mammoth Mountain in Yakutia, the largest region in Siberia.

Fangs for the attention! Four new species of 'smiling' spiders give love bites to females they fancy

Arachnologists at the Senckenberg Research Institute in Frankfurt have identified a new genus of huntsman spider comprised of four new species.

I'm a big boy now! Heart-warming moment baby elephant thinks he is grown up and charges at a safari truck... before changing his mind and hiding under mom

Baby elephant charges at truck before backing away and hiding

The heart-warming footage was captured by a group of tourists to the Kruger National Park in South Africa and shows the moment the elephant calf decides to show his mettle. In the clip the baby runs out from the long grass and goes in for the kill before stopping in his tracks and fleeing into the safety of the long grass and later underneath his mother.

The CYBERDOGS of war: Canines could spy on the enemy using remote-controlled cameras mounted on their backs

The Cerberus Digital Canine Transmitter, developed by Dorset-based Cobham Tactical Communications and Surveillance, is a pop up camera that can be mounted to a dog harness.

Medium claims these images PROVE that the ghost of Richard III now haunts his final resting place

Christine Hamlett, of Northwich, Cheshire, took the photo after visiting the resting place of the 15th century monarch earlier this month

Atomic bonds revealed: Pioneering probe allows scientists to see the electron cloud that holds molecules together

Researchers at the Czech Academy of Science used a fine tipped probe to measure the minute electric forces that surround atoms to unpick what bonds in molecules look like.

Horrifying moment a CENTIPEDE is dragged from a woman's ear canal after it crawled inside while she was sleeping

The unnamed woman arrived at the emergency room of Yangzhou hospital, Jiangsu, China, with the creature in her ear. Doctors killed the bug with saline and dragged it out with tweezers.

The age women are most likely to have cosmetic surgery revealed as 44... and most go under the knife to appear more attractive NOT younger 

Research conducted by The Harley Medical Group found that more than a quarter of British women are unhappy with the way they look and the most desired cosmetic procedure is a tummy tuck.

A 100,000 ton island of steel in the fight against ISIS: Intimate photos capture everyday life for the 5,000 crew living aboard USS Theodore Roosevelt in the Persian Golf

Life on board the USS Theodore Roosevelt aircraft carrier

The USS Theodore Roosevelt, whose homeport is San Diego, California, is a key element of the U.S.-led coalition targeting the militants. This island of steel is in the Persian Gulf. Navy airmen, sailors and Marine pilots, carrying some 70 aircraft are all involved in the fight against the extremists.

Hands off! Chinese students are forced to balance their handsets during military training to 'curb smartphone addiction'

Students at a university in Zhengzhou, central China, were photographed participating in a bizarre training ritual where they had to balance phones on their head and other body parts.

Internet speeds on planes to take off: Aircraft passengers set to enjoy onboard WiFi that is up to 20 TIMES faster

Inflight entertainment is about to go undergo a revolution with the arrival of wifi 20 times faster than the service currently available on US aircraft.

Heart-warming moment male surgeon calms a scared two-year-old girl who sobbed in fear before her heart operation

Photographs emerged of a doctor calming a girl on Chinese social media. Girl was about to have heart surgery in Zhejiang, China, on September 18. Surgeon pictured said it was normal. The girl is recovering well.

'Kate, the Queen and my dog': Prince William reveals wife, close family and his spaniel Lupo would support him against bullies at event honoring Princess Diana

Prince William gave an insight into how close the royal family is at a Diana Awards anti-bullying event. He said he would rely on Harry, Charles and both grandparents in a time of need.

How depression pills turned me into a zombie: This high-flying film-maker ended up needing 24-hour care after being prescribed medication she didn't need

Katinka Blackford-Newman needed 24-hour care after being prescribed antidepressants

When Katinka Blackford Newman, centre, pictured with her two children Lily, 14, and Oscar, 12, was 47, she was prescribed antidepressants following her divorce. She quickly became psychotic, believing she had killed her children on live TV. She spent a year in a catatonic state, and only recovered after stopping taking all medication.

A bit too real? Hundreds of Chinese pupils hospitalised after suffocating in heavy smoke during school fire drill

193 students taken to hospital in Tianshui, China, for smoke inhalation. School used smoke machines to increase realism of September 18 drill. Students have been treated and are stable.

Please signal left or right: Polite Danish pedestrians are urged to indicate what direction they are going at junctions to help drivers

The bizarre practice would mean pedestrians in walking friendly cities such as Copenhagen (pictured) use their arms to point in the direction they intend to turn.

   

DON'T MISS

A flight over Pluto's icy mountains: Striking animation reveals intricate details of the dwarf planet's 'Arctic' terrain

Fly over Pluto’s icy mountains in stunning new animation

Last week, Nasa released stunning new images of Pluto majestic mountains, frozen nitrogen rivers and low-lying hazes. Now, the space agency has combined these panoramas to create a spectacular flyover of the dwarf planet, revealing its icy terrain in incredible detail. The animation begins just above the mountains dubbed Norgay Montes region at a height of about 120 miles (200 km) (top left). It then flies north over Pluto's Sputnik Planum and Cthulhu Regio regions (bottom left and right).

Father takes his three young children 'storm chasing' in an armored 'TANK' called Dominator 3 to capture photos of America's supercells and tornadoes

Mike Olbinski, from Phoenix, Arizona, spends almost all of his free-time photographing extreme weather formations, often traveling hundreds of miles in an armoured 'tank' to remote areas of America.

Couple's car left in tatters after a bear LOCKED himself inside and tried to claw his way out

Colorado couple's car left in tatters after a bear manages to LOCK himself inside

A Colorado couple's car was ruined over the weekend after a wild bear managed to get inside and maul its interior to bits. Karl Andersen of Jefferson County is now in the market for a new car after waking up to some strange noises around 3:30 a.m. on Sunday and finding the animal clawing away at his driver's seat. Not only had the bear managed to get the door open, but it somehow managed to then hit the lock behind him, KUSA reports.

WORLD NEWS

An eight-month-old baby lies on Eftalou beach        

The hermit crab forced to live in a toothpaste cap: Heartbreaking image shows the harsh reality of Earth's plastic pollution

Hermit crab forced to live in toothpaste cap: Image shows the reality of plastic pollution

Homeless and desperate, this hermit crab has resorted to using a toothpaste lid to protect its body. It's a heartbreaking scene which reveals the harsh reality of plastic pollution and what it's doing to Earth's sea creatures. According to recent estimates, the ocean is filled with eight million tonnes of garbage - enough to fill five carrier bags for every foot of coastline on the planet. The image was uploaded by Reddit user Hscmidt after his girlfriend spotted the tiny crab roaming a beach in Cuba.

Happy BEAR-thday! World's oldest male panda Pan Pan turns 30 and celebrates with a yummy ice cake

Pan Pan was a wild panda born in 1985 in Sichuan, south west China. He now lives at China Giant Panda Protection and Research Centre. The bear has fathered 130 cubs and has been dubbed 'hero dad'.

'I need $6 for candy': Children reveal how much money would make them feel wealthy

A group of kids were polled in New York's Times Square about how much money they would need to feel rich, and most of the children revealed that small sums would make them feel wealthy.

Three-month-old mountain lion left fighting for his life after suffering devastating burns to his paws and face during California wildfire

The 'fragile' three-month-old cub was discovered on a road in Calaveras County south east of Sacramento by volunteers who were evacuating domestic animals in the area.

A elevator with a view! Chinese park installs spectacular $3million glass lift

A Chinese national park in Hubei Province has installed a set of glass lifts on the side of a near-vertical cliff. The 20 million Yuan (£2 million) project was put into operation on September 1.

Earning its stripes: Ruthless crocodiles attack migrating zebra and eat it alive as it attempts to cross river in Kenya

Nile Crocodiles attack and eat a migrating zebra as it crosses river in Kenya

A group of Nile crocodiles have been photographed attacking a migrating zebra then eating it alive while it desperately attempts to cross a river to safety. Taken by wildlife photographer Paolo Torchio, 54, the pictures show the crocodiles swarming around the zebra after it was first attacked, then ripping it to pieces in the water. The dramatic scenes unfolded on the Mara River, in Kenya's Maasai Mara National Reserve, which is regularly crossed by migrating zebra and wildebeest - but also home to hundreds of crocodiles.

   

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