UniProtKB - A8MTA8 (F166B_HUMAN)
UniProt
A8MTA8 - F166B_HUMAN
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Protein
Protein FAM166B
Gene
FAM166B
Organism
Homo sapiens (Human)
Sequence features
Status
Names & Taxonomyi
Protein namesi | Recommended name: Protein FAM166B |
Gene namesi | Name:FAM166B |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi | UP000005640: Chromosome 9 Componenti |
Organism-specific databases
HGNCi | HGNC:34242. FAM166B. |
Pathology & Biotechi
Organism-specific databases
PharmGKBi | PA162387040. |
Polymorphism and mutation databases
BioMutai | FAM166B. |
PTM / Processingi
Molecule processing
Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
---|---|---|---|---|---|---|
Chaini | 1 – 275 | 275 | Protein FAM166B | PRO_0000342383 | Add BLAST |
Proteomic databases
PaxDbi | A8MTA8. |
PRIDEi | A8MTA8. |
PTM databases
PhosphoSitei | A8MTA8. |
Expressioni
Gene expression databases
Bgeei | A8MTA8. |
CleanExi | HS_FAM166B. |
ExpressionAtlasi | A8MTA8. baseline and differential. |
Genevisiblei | A8MTA8. HS. |
Organism-specific databases
HPAi | HPA045540. |
Family & Domainsi
Sequence similaritiesi
Belongs to the UPF0605 family.Curated
Phylogenomic databases
eggNOGi | ENOG410IPQ1. Eukaryota. ENOG4111J2F. LUCA. |
GeneTreei | ENSGT00730000111299. |
HOGENOMi | HOG000231525. |
HOVERGENi | HBG070076. |
InParanoidi | A8MTA8. |
OMAi | TYPQNLG. |
OrthoDBi | EOG75QR4N. |
PhylomeDBi | A8MTA8. |
TreeFami | TF325739. |
Family and domain databases
InterProi | IPR018902. UPF0573/UPF0605. [Graphical view] |
Pfami | PF10629. DUF2475. 2 hits. [Graphical view] |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basket
Isoform 1 (identifier: A8MTA8-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
10 20 30 40 50
MAVASTFIPG LNPQNPHYIP GYTGHCPLLR FSVGQTYGQV TGQLLRGPPG
60 70 80 90 100
LAWPPVHRTL LPPIRPPRSP EVPRESLPVR RGQERLSSSM IPGYTGFVPR
110 120 130 140 150
AQFIFAKNCS QVWAEALSDF THLHEKQGSE ELPKEAKGRK DTEKDQVPEP
160 170 180 190 200
EGQLEEPTLE VVEQASPYSM DDRDPRKFFM SGFTGYVPCA RFLFGSSFPV
210 220 230 240 250
LTNQALQEFG QKHSPGSAQD PKHLPPLPRT YPQNLGLLPN YGGYVPGYKF
260 270
QFGHTFGHLT HDALGLSTFQ KQLLA
Alternative sequence
Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
---|---|---|---|---|---|---|
Alternative sequencei | 183 – 239 | 57 | FTGYV…LGLLP → TAGIWAEALTRQCPGPQTSP PTSQNIPSEPGSFT in isoform 2. 1 Publication | VSP_034438 | Add BLAST | |
Alternative sequencei | 240 – 275 | 36 | Missing in isoform 2. 1 Publication | VSP_034439 | Add BLAST |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL133476 Genomic DNA. Translation: CAX14972.1. BC129999 mRNA. Translation: AAI30000.1. BC146928 mRNA. Translation: AAI46929.1. BC146933 mRNA. Translation: AAI46934.1. |
CCDSi | CCDS47963.1. [A8MTA8-2] CCDS56572.1. [A8MTA8-1] |
RefSeqi | NP_001093421.1. NM_001099951.3. [A8MTA8-2] NP_001157782.1. NM_001164310.2. [A8MTA8-1] NP_001274168.1. NM_001287239.1. |
UniGenei | Hs.98959. |
Genome annotation databases
Ensembli | ENST00000399742; ENSP00000382646; ENSG00000215187. [A8MTA8-1] ENST00000447837; ENSP00000412746; ENSG00000215187. [A8MTA8-2] |
GeneIDi | 730112. |
KEGGi | hsa:730112. |
UCSCi | uc003zwy.3. human. [A8MTA8-2] uc010mkr.3. human. [A8MTA8-1] |
Keywords - Coding sequence diversityi
Alternative splicingCross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL133476 Genomic DNA. Translation: CAX14972.1. BC129999 mRNA. Translation: AAI30000.1. BC146928 mRNA. Translation: AAI46929.1. BC146933 mRNA. Translation: AAI46934.1. |
CCDSi | CCDS47963.1. [A8MTA8-2] CCDS56572.1. [A8MTA8-1] |
RefSeqi | NP_001093421.1. NM_001099951.3. [A8MTA8-2] NP_001157782.1. NM_001164310.2. [A8MTA8-1] NP_001274168.1. NM_001287239.1. |
UniGenei | Hs.98959. |
3D structure databases
ProteinModelPortali | A8MTA8. |
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
STRINGi | 9606.ENSP00000382646. |
PTM databases
PhosphoSitei | A8MTA8. |
Polymorphism and mutation databases
BioMutai | FAM166B. |
Proteomic databases
PaxDbi | A8MTA8. |
PRIDEi | A8MTA8. |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
Ensembli | ENST00000399742; ENSP00000382646; ENSG00000215187. [A8MTA8-1] ENST00000447837; ENSP00000412746; ENSG00000215187. [A8MTA8-2] |
GeneIDi | 730112. |
KEGGi | hsa:730112. |
UCSCi | uc003zwy.3. human. [A8MTA8-2] uc010mkr.3. human. [A8MTA8-1] |
Organism-specific databases
CTDi | 730112. |
GeneCardsi | FAM166B. |
HGNCi | HGNC:34242. FAM166B. |
HPAi | HPA045540. |
neXtProti | NX_A8MTA8. |
PharmGKBi | PA162387040. |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG410IPQ1. Eukaryota. ENOG4111J2F. LUCA. |
GeneTreei | ENSGT00730000111299. |
HOGENOMi | HOG000231525. |
HOVERGENi | HBG070076. |
InParanoidi | A8MTA8. |
OMAi | TYPQNLG. |
OrthoDBi | EOG75QR4N. |
PhylomeDBi | A8MTA8. |
TreeFami | TF325739. |
Miscellaneous databases
GenomeRNAii | 730112. |
NextBioi | 132312. |
PROi | A8MTA8. |
Gene expression databases
Bgeei | A8MTA8. |
CleanExi | HS_FAM166B. |
ExpressionAtlasi | A8MTA8. baseline and differential. |
Genevisiblei | A8MTA8. HS. |
Family and domain databases
InterProi | IPR018902. UPF0573/UPF0605. [Graphical view] |
Pfami | PF10629. DUF2475. 2 hits. [Graphical view] |
ProtoNeti | Search... |
Publicationsi
- "DNA sequence and analysis of human chromosome 9."
Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. Dunham I.
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. - "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).Tissue: Brain cortex.
Entry informationi
Entry namei | F166B_HUMAN | ||||||||
Accessioni | A8MTA8Primary (citable) accession number: A8MTA8 Secondary accession number(s): A1L3B2, B7ZBJ0 | ||||||||
Entry historyi |
| ||||||||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Annotation program | Chordata Protein Annotation Program | ||||||||
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- Human chromosome 9Human chromosome 9: entries, gene names and cross-references to MIM
- SIMILARITY commentsIndex of protein domains and families
- Uncharacterized protein families (UPF)List of uncharacterized protein family (UPF) entries
External Data
Dasty 3Similar proteinsi
Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:100% | UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry. |
90% | UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence). |
50% | UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster. |